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Symptoms of severe aplastic anemia (SAA) are caused by low numbers of blood cells. With very low numbers, the symptoms listed below will be severe. With only moderately low numbers, these symptoms will be less severe.

  • Low numbers of red blood cells cause weakness and fatigue (tiredness), shortness of breath, and unusually pale skin
  • Low numbers of white blood cells can lead to frequent or severe infections
  • Low numbers of platelets can lead to easy bleeding or bruising, bleeding that is hard to stop, and tiny red spots on the skin (petechiae)
  • In severe or very severe aplastic anemia, infections or bleeding can be life-threatening and require immediate medical attention.

Learn how transplant can treat SAA.

MedlinePlus [Internet]. Bethesda (MD): National Library of Medicine (US); [updated 2013 Sept 16; cited 2013 Sept 16]. Available from: