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Early-Onset GLD

Symptoms of early-onset GLD usually appear in babies between 2 and 12 months of age. Symptoms include:

  • Unexplained crying
  • Unexplained fevers
  • Stiffness
  • Seizures, or fits of uncontrolled movement
  • Slow development

These symptoms get worse quickly, and children with GLD usually die before the age of 2 years. 

Late-Onset GLD

Late-onset GLD can appear in people of any age. The symptoms include:

  • Weakness
  • Stiffness
  • Problems seeing
  • Problems walking
  • Loss of mental ability

These symptoms may worsen quickly, as in early-onset GLD, or slowly over many years.

Learn how transplant can treat GLD.

MedlinePlus [Internet]. Bethesda (MD): National Library of Medicine (US); [updated 2013 Sept 16; cited 2013 Sept 16]. Available from: