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Chronic lymphocytic leukemia (CLL) often develops slowly, and some people with CLL do not have any symptoms of the disease when they are diagnosed. For these people, a doctor may order more testing after a routine blood test shows changes in the blood. Other people might have the following symptoms:

  • Enlarged, but painless, lymph nodes
  • Abdominal pain or a feeling of fullness (caused by an enlarged spleen or liver)
  • Fatigue (tiredness)
  • Fever
  • Night sweats
  • Weight loss
  • Frequent infections

Learn how transplant can treat CLL.

MedlinePlus [Internet]. Bethesda (MD): National Library of Medicine (US); [updated 2013 Sept 16; cited 2013 Sept 16]. Available from: